Duboisia Myoporoides dubo-m.

Corkwood Elm (DUBOISIA)

Acts chiefly on the nervous system, eyes, upper respiratory tract. Recommended in pharyngitis sicca, with black, stringy mucus. It dilates the pupil, dries the mouth, checks perspiration, causes headache and drowsiness. On the eye it acts more promptly than Atropia, much stronger as a mydriatic. Red spots floats in the field of vision. Sensation as if stepping on empty space. Vertigo with pale face; not gastric in origin. Scarlet fever; locomotor ataxia. Palliative in exophthalmic goitre.

Absent-minded, incoherent, silly and nonsensical, memory impaired.

Impossible to stand with eyes shut, tendency to fall backwards.

Conjunctivitis, acute and chronic. Mydriasis. Paralysis of accommodation. Hyperæmia of retina with weakness of accommodation, fundus red, blood-vessels full and tortuous; pupils dilated, with dim vision. Pain over eye, between it and brow.

Larynx dry, voice hoarse, phonation difficult. Dry cough with oppressed breathing.

Loss of power in limbs, staggers; feels as if he stepped on empty space. Trembling, numbness and weakness.

It antagonizes Muscarine. Duboisin sulphate 1-100 gr sedative in mania. 2-4 milligrams a day. Hystero-epilepsy. Motor restlessness of insane (Has been used as a substitute for Atropia in doses of 1-20 of a grain hypodermically). Antidotes: Morphia; Pilocarp. Compare: Bellad; Stram; Hyos.

Third to twelfth potency.

A tincture is made of the dry leaves of Duboisia myoporoides, R. Br. These contain the alkaloid -Duboisine- from which most of the effects have been observed.

Almost identical (as far as known) with Belladonna.

Belladonna, Stramon.

Trembling. ▶ Intoxicated appearance. ▶ Restlessness; in afternoon. ▶ Ineffectual efforts to sit up in bed. ▶ Weakness all afternoon. ▶ Faintness. ▶ Asleep sensation in legs, then in thighs, arms and other parts, afterwards patient could hardly talk or stand. ▶ Lemon-juice acted as an antidote.

Delirium, with tendency to pick at surrounding objects drawing up of arms, restlessness, rapid pulse, heat attempt to get up. ▶ Hallucination. ▶ Fidgety. ▶ Stupor, with weakness as if he had no life in him. ▶ Unable to concentrate thoughts. ▶ Absent-minded, thoughts wander from one subject to another, but all are silly and nonsensical. ▶ Memory lost. ▶ Unconsciousness. ▶ Carphology, suspicious glancing beneath the bed-clothes and behind the back, incessant activity, the whole room was upset, flow of disconnected sentences, memory of things that happened years ago, an air of fun and humor, symptoms of childishness rather than of violent imagined it was dark, afterwards unconsciousness of what had occurred.

Inability to hold it up. ▶ Aching over eyes, in forehead and temples; over left eye. ▶ Dullness as after interrupted sleep. ▶ Heaviness. ▶ Strange feeling. ▶ Vertigo; on rising up or walking the legs seem unable to bear the body, staggering, but can walk straight by concentrating mind on the action and watching steps, inclination to fall backward, agg. ascending stairs, almost impossible to stand with eyes shut, constantly swaying backward and forward, obliged to be held by another when eyes are closed.

Pain; when reading, cold read better and print looked blacker at double the usual distance, eyes feel tired, sharp pain in upper part of ball, afterwards paralysis of accommodation, could not bear to read at any distance, could not look at food when eating on account of pain. ▶ Hot and tired; hot and dry, also face, lids œdematous. ▶ Cool feeling; in evening. ▶ Lachrymation. ▶ Pupils dilated; irregularly, apparently in segments; ovoid, afterwards nearly round; dilatation grows less as paralysis of accommodation increases; pupil vertically ovoid and irregular, in response to change of light and shadow the least dilated parts show the most movement, at ten minutes it is firmly contracted everywhere, except at temporal side, and is irregularly round, at twelve minutes it is contracted evenly all around, sees horizontal lines best.

Disc very red, small vessels of disc visible, larger vessels enlarged, and tortuous, outline of disc indistinct, retinal veins dilated, arteries diminished, whole fundus hyperæmic, accommodation paralyzed, could not read Jager No. 1 at any distance, but with + 36 could read it at twelve inches, any change in distance causing blur. ▶ Smarting sharp pain in upper part of ball. ▶ On looking up from book pain in upper part of balls and in forehead similar to sick headache, and eyes feel large and protruding. ▶ Lids agglutinated in morning. ▶ Palpebral orifices contracted all day.

Photophobia. ▶ Things seem elevated. ▶ Letters ran together in evening when reading. ▶ Vision misty for near objects. ▶ Accommodation paralyzed; soon and before the pupil was fully dilated and continued when it had regained its normal size; cannot read at any distance, can read with + 20 glasses. ▶ Cannot make out print within two feet of me, print shows blue, orange and reddish-brown, can see to read with + 20 glasses, but glass strained the eyes.

Neuro-retinitis. ▶ Exophthalmic goitre.

Earache in morning. ▶ Left ear felt as if water were in it, a dull feeling. ▶ Sudden ringing in ears, agg. right. ▶ Nose stopped; and dry. ▶ Smarting sharp pain down right side of face.

Dryness; and of tongue; and throat amel. lemon-juice; of M. and throat in afternoon, agg. lips, temporarily amel. water, constantly thirsty for large quantities frequently repeated; of M., throat and tongue, with stickiness, but not much desire for water. ▶ Taste bad; bitter.

Patches of partially translucent, adherent, yellowish-white mucus in pharynx. ▶ Pain as from a splinter in left side on swallowing agg. empty S. ▶ Dryness; agg. back part; with burning and cough; without much thirst; pharynx dry and hyperæmic, purple-red, capillaries much engorged, here and there varicosities, follicles very prominent and configuration of spinal column readily distinguishable, a picture of pharyngitis sicca.

Appetite lost. ▶ Nausea; all the afternoon. ▶ Deadly, gone feeling all afternoon, as if at greater curvature, not amel. eating or drinking. ▶ Sick feeling, general faintness, agg. epigastric region, head light as if intoxicated face feels warm but is not flushed, mouth and throat dry, saliva scanty and viscid, giddiness on walking, it seemed as if I could not control all parts of body at the same time pain in forehead, pulse 52, full, occasionally at rate of 80 for a few beats.

Burning in urethra during micturition. ▶ Urine increased.

Epiglottis hyperæmic, agg. vicinity of glosso-epiglottidean folds, membrane lining larynx engorged, dry, with patches of viscid, semi-translucent, adherent mucus, appearing like a pseudo membrane, the hyperæmia agg. along course of ary-epiglottidean folds, the membrane covering cartilages of Wrisberg, the capitula Santorini and the interarytænoidal commissure, in the last-mentioned localities the most of the dry, translucent discharge was seen, vocal cords congested, agg. near posterior commissure, mucus adherent to their free borders, forming narrow bands that stretched from side to side when the cords were widely separated in deep inspiration. ▶ Hoarseness; and phonition difficult, constant desire to clear throat, generally unsuccessful; voice husky and indistinct.

Cough increased (have always had a C., but not so severe as this), next morning hard dry, hacking from tickling at bifurcation of trachea, cough causes soreness or rawness over lungs, agg. lower lobe of left and upper lobe of right.

Rapid; varied from 108 to 112, but always fell to 80 when the patient was supported in a sitting posture and increased again on reclining. ▶ Slow. ▶ Intermittent; and feeble. ▶ Strong full, regular.

Heaviness, agg. lower. ▶ Weakness of arms and legs. ▶ Jerking of muscles of arm on extending hand to grasp anything. ▶ Right hand and fingers feel as if going to sleep. ▶ Gait unsteady, occasionally feeling as if I stepped on empty space, and I would catch myself for fear of falling. ▶ Right knee sore below patella, as if strained or rheumatic. ▶ Lower limbs tingle as if asleep.

Gaping and sneezing all day. ▶ Drowsiness. ▶ Night restless, could not get to sleep for hours, had to get up for water every five minutes. ▶ Chilliness. ▶ Heat; agg. internally.